• Elastin Products Company, Inc.
    P.O. Box 568
    Owensville, Missouri, USA 65066

  • Phone: 573-437-2193
    Fax: 573-437-4632

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DESCRIPTION.Purified from bovine neck ligament (ox ligamentum nuchae) by proprietary hydrolysis method. Generally, the ligament is manually freed of gross connective tissue, fat and muscle then pulverized. The mulch is boiled in water to remove soluble proteins then boiled in alkali to remove resistant proteins. The washed insoluble mulch is hydrolyzed and further purified by cellulose chromatography and lyophilized. Hygroscopic.


Elastin No. CB573 is highly soluble in water, buffers and detergents; greater than 200 mg/ml. The molecular weight range by gel filtration chromatography is 1,000 to 60,000 indicating a mixture of peptides. About 60% pass a 3KDa MWCO hollow fiber at 6 psi. These peptides contain the cross-linked amino acids desmosine and isodesmosine and the repeating peptide Val-Gly-Val-Ala-Pro-Gly. Similarly prepared elastin peptides have been reported to stimulate migration of human skin fibroblasts, Senior,,(77).